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Indoor and Built Environment
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Tobacco-Specific and Volatile N-Nitrosamines in Environmental Tobacco Smoke of Offices

Hubert Klus

Ökolab Gesellschaft für Umweltanalytik mbH, Wien, Österreich

Helmut Begutter

Ökolab Gesellschaft für Umweltanalytik mbH, Wien, Österreich

Gerhard Scherer

Analytisch-Biologisches Forschungslabor Prof. Dr. Adlkofer, München, BRD

Anthony R. Tricker

Analytisch-Biologisches Forschungslabor Prof. Dr. Adlkofer, München, BRD

Franz Adlkofer

Analytisch-Biologisches Forschungslabor Prof. Dr. Adlkofer, München, BRD

The tobacco-specific nitrosamines (TSNA) N-nitrosonornicotine (NNN) and 4-(N-methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) as well as the vola tile N-nitrosamines N-nitrosodimethylamine (NDMA) and N-nitrosopyrrol idine (NPYR) were determined in the indoor air of a poorly ventilated office where extensive smoking took place. Under these conditions, moderate to heavy smoking resulted in indoor air concentrations of 7.6-20.0 ppm carbon monoxide, 109-290 ppb nitrogen oxides and 58.5-132 µg/m 3 nicotine. The N-nitrosamine concentrationes were (in nanograms/cubic meter): not de tected (nd)-6.0 NNN, nd-13.5 NNK, 7.9-45.0 NDMA and 3.5-27.0 ng/m3 NPYR. Occupation of the office by a nonsmoker for 1 h would result in a maximum exposure to 0.01 µg TSNA and 0.03 µg volatile N-nitrosamines.

Key Words: Environmental tobacco smoke • Tobacco-specific nitrosamine • Indoor air

Indoor and Built Environment, Vol. 1, No. 6, 348-350 (1992)
DOI: 10.1177/1420326X9200100606
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