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Indoor and Built Environment
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Prevalence of Impaired Lung Function in Rubber Manufacturing Factory Workers Exposed to Benzo(a)pyrene and Respirable Particulate Matter

Pratibha Gupta

Department of Physiology, University College of Medical Sciences and G.T.B. Hospital, Delhi

D.K. Banerjee

School of Environmental Sciences, Jawaharlal Nehru University, New Delhi

S.K. Bhargava

Department of Radiology, University of Medical Sciences and G.T.B. Hospital, Delhi, India

Rajni Kaul

Department of Physiology, University College of Medical Sciences and G.T.B. Hospital, Delhi

V. Ravi Shankar

Department of Physiology, University College of Medical Sciences and G.T.B. Hospital, Delhi

The respiratory health of 726 workers in a rubber processing factory has been investigated. The values of the forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and the ratio of FEV1/FVC in workers were inversely related to the total suspended particulate matter (TSP) and benzo(a)pyrene present in the workplace air. Statistically significant decrements in ventilatory function occurred following prolonged exposure as assessed by the duration of working in the plant. When the different sections of the factory were consid ered, workers in the compounding section were most affected, which was asso ciated with the highest exposures to TSP and benzo(a)pyrene. On chest X-ray, 16 % of the workers from the compounding section exhibited radiographic abnormalities. Of 7 possible factors thought likely to be related to the effects on pulmonary function, only TSP and the concentration of benzo( a)pyrene in the respirable fraction of particulates resulted in a statistically significant asso ciation in a multiple regression analysis.

Key Words: Rubber factory workers • Pulmonary function • Forced expiratory volume • Suspended particulate matter • Benzo(a)pyrene • Radiological abnormalities

Indoor and Built Environment, Vol. 2, No. 1, 26-31 (1993)
DOI: 10.1177/1420326X9300200105
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