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Indoor and Built Environment
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Polyvinyl-Chloride-Induced Lung Disease

Bela Szende

Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest, Hungary

The first histologically and clinically documented case of pneumoconiosis caused by prolonged polyvinyl chloride (PVC) inhalation was described in 1970. A series of human epidemiological as well as some experimental studies confirmed the existence of PVC pneumoconiosis. Pyrolytic products of PVC, of vinyl chloride and of plasticisers and stabilisers may irritate the respiratory organs, causing fibrosis, asthma, bronchitis and even cancer of the lung. Work ers employed in PVC plants are at high risk with respect to PVC-induced lung disease.

Key Words: Polyvinyl chloride • Vinyl chloride monomer • Pneumoconiosis

Indoor and Built Environment, Vol. 3, No. 4, 248-253 (1994)
DOI: 10.1177/1420326X9400300411
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